Cytogenetics and molecular genetics of hematological malignancies
Conventional (karyotype) and molecular (FISH) cytogenetic analyses of hematological malignancies for the identification and characterization of chromosomal abnormalities in hematologic malignancies.
Characterization of genomic rearrangements in hematologic malignancies by molecular genetics for diagnosis, prognosis, treatment selection and follow up of the patients.
Discrimination of early and late leukemia-associated genomic lesions in order to elucidate aberrations responsible for disease evolution.
Investigation of polymorphisms of detoxifying and DNA repair genes as predisposing factors for the development of human malignancy.
Epigenetic analysis of malignant hemopathies for the elucidation of genetic mechanisms involved in leukemogenesis.