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Biodiagnostic Sciences and Technologies
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Cytogenetics and molecular genetics of hematological malignancies

  • Conventional (karyotype) and molecular (FISH) cytogenetic analyses of hematological malignancies for the identification and characterization of chromosomal abnormalities in hematologic malignancies.
  • Characterization of genomic rearrangements in hematologic malignancies by molecular genetics for diagnosis, prognosis, treatment selection and follow up of the patients.
  • Discrimination of early and late leukemia-associated genomic lesions in order to elucidate aberrations responsible for disease evolution.
  • Investigation of polymorphisms of detoxifying and DNA repair genes as predisposing factors for the development of human malignancy.
  • Epigenetic analysis of malignant hemopathies for the elucidation of genetic mechanisms involved in leukemogenesis.