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Biomolecular Physics Publications

› S. Pyrpassopoulos, A. Ladopoulou, M. Vlassi, Y. Papanikolau, C. E. Vorgias, D. Yannoukakos and G. Nounesis, “Thermal denaturation of the BRCT tandem repeat region of the human tumour suppressor gene product BRCA1”, Biophysical Chemistry 114, 1 (2005)

› G. Cordoyiannis, G. Nounesis, V. Bobnar, S. Kralj, and Z. Kutnjak, “Confinement-induced orientational order in a ferroelectric liquid crystal containing dispersed aerosols”, Physical Review Letters 94, 027801 (2005)

› Z. Kutnjak, G. Cordoyiannis, G. Nounesis, A. Lebar, and S. Žumer, “Calorimetric study of phase transitions in a liquid-crystal-based microemulsion,” The Journal of Chemical Physics 122, 224709 (2005)

› I. Tsogas, D. Tsiourvas, C.M. Paleos, S. Giatrellis and G. Nounesis, “Interaction of l-arginine with dihexadecylphosphate unilamellar liposomes: the effect of the lipid phase organization”, Chemistry and Physics of Lipids 134, 59 (2005)

› I. Tsogas, D. Tsiourvas, C.M. Paleos, S. Giatrellis and G. Nounesis, “Interaction of Poly-l-arginine with Dihexadecyl Phosphate/Phosphatidylcholine Liposomes”, Langmuir 21, 5997 (2005)

› A. Pantos, D. Tsiourvas C. M. Paleos and G. Nounesis, “Enhanced drug transport from unilamellar to multilamellar liposomes induced by molecular recognition of their lipid membranes”, Langmuir 21, 6696 (2005)

› A. Pantos, D. Tsiourvas, G. Nounesis and C. M. Paleos “Interaction of Functional Dendrimers with Multi-lamellar Liposomes: Design of a Model System for Studying Drug Delivery”, Langmuir 21, 7483 (2005)

› E. G. Kapetaniou, A. Thanassoulas, A. P. Dubnovitsky, G. Nounesis and A. C. Papageorgiou “Effect of pH on the structure and stability of Bacillus circulans ssp. alkalophilus phosphoserine aminotransferase: Thermodynamic and crystallographic studies”, Proteins: Structure, Function and Bioinformatics 63, 742 (2006)

› G. Cordoyiannis, S. Kralj, G. Nounesis, S. Zumer and Z. Kutnjak, “Soft-stiff regime crossover for an aerosil network dispersed in liquid crystals”, Physical Review E, Statistical, Nonlinear and Soft Matter Physics 73, 031707 (2006)

› S. Pyrpassopoulos, M. Vlassi, A. Tsortos, Y. Papanikolau, K. Petratos, C.E. Vorgias and G. Nounesis, “Equilibrium heat-induced denaturation of Chitinase 40 from Streptomyces Thermoviolaceus”, Proteins: Structure, Function and Bioinformatics 64, 513 (2006)

› I. Tsogas, D. Tsiourvas, G. Nounesis and C.M. Paleos, “Modelling cell membrane transport: interaction of guanidinylated poly(propylene imine) dendrimers with a liposomal membrane consisting of phosphate based lipids”, Langmuir 22, 11322 (2006)

› G. Cordoyiannis, G. Nounesis, Z. Kutnjak, and S. Kralj, “Randomness in aerosil disordered liquid crystals”, in Phase Transitions. Applications to Liquid Crystals, Organic Electronic and Optoelectronic Fields, V. Popa-Nita Editor,Research Signpost, Kerala, (2006)

› G. Cordoyiannis, S. Kralj, G. Nounesis, Z. Kutnjak and S. Zumer “Pretransitional effects near the Smectic-A – Smectic-C* phase transition of hydrophilic and hydrophobic aerosil networks dispersed in ferroelectric liquid crystals”, Physical Review E, Statistical, Nonlinear and Soft Matter Physics 75, 021702 (2007)

› G. Nikolopoulos, S. Pyrpassopoulos, A. Thanassoulas, P. Klimenzou, C. Zikos, M. Vlassi, C. E. Vorgias, D. Yannoukakos and G. Nounesis, “Thermal unfolding of human BRCA1 BRCT-domain variants”, Biochimica et Biophysica Acta, Proteins & Proteomics 1774, 772 (2007)

› S. Pyrpassopoulos, D. Niarchos, G. Nounesis, N. Boukos, I Zafiropoulou and V. Tzitzios, “Synthesis of Au nanoparticles – 2D and 3D organization”, Nanotechnology 18, 485604 (2007)

› I. Konstantopoulou, T. Rampias, A. Ladopoulou, G. Koutsodontis, S. Armaou, T. Anagnostopoulos, G. Nikolopoulos, S. Kamakari, G. Nounesis, A, Stylianakis, C. Karanikiotis, E. Razis, H. Gogas, A. Keramopoulos, V. Gaki, C. Markopoulos, D. Skarlos, N. Pandis, T. Bei, I. Arzimanoglou, G. Fountzilas and D. Yannoukakos, “Greek BRCA1 & BRCA2 mutation spectrum: Two BRCA1 mutations account for half the carriers found among high-risk breast/ovarian cancer patients”, Breast Cancer Research & Treatment 107, 431 (2008)

› A. Chroni, S. Pyrpassopoulos, A. Thanassoulas, G. Nounesis, V.I. Zannis and E. Stratikos, “Biophysical analysis of progressive C-terminal truncations of human apolipoprotein E4: insights into secondary structure and unfolding properties”, Biochemistry 47, 9071 (2008)

› F. Orfaniotou, P. Tzamalis, A. Thanassoulas, E. Stefanidi, A. Zees, E. Boutou, M. Vlassi, G. Nounesis and C.E. Vorgias, “The stability of the archaeal HU histone-like DNA-binding protein from Thermoplasma Volcanium”, Extremophiles 13, 1 (2009)

› S. Giatrellis, G. Nikolopoulos, Z. Sideratou and G. Nounesis, “Thermodynamic study of the interaction of cationic binary-lipid liposomes with plasmid DNA”, Journal of Liposome Research, 19, 220 (2009)

› G. Cordoyiannis, A. Zidansek, G. Lahajnar, Z. Kutnjak, H. Amenitsch, G. Nounesis and S. Kralj, “Influence of the controlled-porous glass confinement on the layer spacing of smectic-A liquid crystals”, Physical Review E, Statistical, Nonlinear and Soft Matter Physics 79, 051703 (2009)

› I. Drikos, G. Nounesis and C.E. Vorgias, “Characterization of cancer-linked BRCA1-BRCT missense variants and interaction with phosphoprotein targets”, Proteins, Structure, Function, and Bioinformatics 77, 464 (2009)

› A.C. Zees, S. Pyrpassopoulos and C.E. Vorgias, “Insights into the role of the (alpha+beta) insertion in the TIM-barrel catalytic domain, regarding the stability and the enzymatic activity of chitinase A from Serratia marcescens”, Biochimica et Biophysica Acta, Proteins and Proteomics 1794, 23 (2009)

› E. Karatairi, B. Rozic, V. Tzitzios, G. Nounesis, Z. Kutnjak, G. Cordoyiannis, J. Thoen, C. Glorieux and S. Kralj "Nanoparticle-induced widening of the temperature range of liquid-crystalline blue phases", Physical Review E, Statistical, Nonlinear and Soft Matter Physics 81, 041703 (2010)

Paper selected for the Virtual Journal of Nanoscale Science and Technology, American Institute of Physics, May 10, 2010 (http://scitation.aip.org/nano/)

› A. Thanassoulas, M. Nomikos, M. Theodoridou, D. Yannoukakos, D. Mastellos and G. Nounesis, “Thermodynamic study of the BRCT domain of BARD1 and its interaction with the –pSer-X-X-Phe- motif-containing BRP1 peptide”, Biochimica et Biophysica Acta, Proteins & Proteomics 1804, 1908 (2010)

› Z. Sideratou, N. Sterioti, D. Tsiourvas, L.A. Tziveleka, A. Thanassoulas, G. Nounesis and C.M. Paleos, “Arginine end-functionalized poly(L-lysine) dendrigrafts for the stabilization and controlled release of insulin”, Journal of Colloid and Interface Science 351, 433 (2010)

› K. Misiakos, P.S. Petrou, S.E. Kakabakos, D. Yannoukakos, H. Contopanagos, T. Knoll, T. Velten, M. Defazio, L. Schiavo, M. Passamano, D. Stamou and G. Nounesis,“Fully integrated monolithic optoelectronic transducer for real-time protein and DNA detection: The NEMOSLAB approach”, Biosensors and Bioelectronics 26, 1538 (2010)

› G. Cordoyiannis, P. Losada-Perez, C.S.P. Tripathi, B. Rozic, U. Tkalec, V. Tzitzios, E. Karatairi, G. Nounesis, Z. Kutnjak, I. Musevic, C. Glorieux and J. Thoen, “Blue phase III widening in CE6 with dispersed surface-functionalized nanoparticles”, Liquid Crystals 37, 1419 (2010)

› T. Haikarainen, A. Thanassoulas, P. Stavros, G. Nounesis, S. Haataja and A.C. Papageorgiou, “Structural and thermodynamic characterization of metal ion binding in Streptococcus suis Dpr”, Journal of Molecular Biology 405, 448 (2011)

› K. Fotiadou, A. Thanassoulas, G. Nounesis and K. Yannakopoulou, “Cooperative heterodimer formation between per-guadinylated and carboxylated or phosphorylated cyclodextrins in DMSO and DMSO–water studied by NMR spectroscopy and microcalorimetry", Supramol. Chem. 23, 493 (2011)

› A. Thanassoulas, M. Nomikos, M. Theodoridou, D. Mastellos, P. Stavros and G. Nounesis, “Thermal and chemical denaturation of the BRCT functional module of human 53BP1”, International Journal of Biological Macromolecules 49, 297 (2011)

› S. Giatrellis and G. Nounesis, “Nucleic acid – membrane interactions studied by differential scanning calorimetry”, an Invited Review Paper, Journal of Pharmacy and Bioallied Sciences 3, 70 (2011)

› B. Rozic, V. Tzitzios, E. Karatairi, U. Tkalec, G. Nounesis, Z. Kutnjak, G. Cordoyiannis, R. Rosso, E.G. Virga, I. Musevic, and S. Kralj, “Theoretical and experimental study of the nanoparticle-driven blue phase stabilization”, The European Physical Journal E: Soft Matter and Biological Physics 34, 17 (2011)

› M. Karayianni, S. Pispas, G.D. Chryssikos, V. Gionis, S. Giatrellis and G. Nounesis, “Complexation of Lysozyme with Sodium(Sulfamate-Carboxylate) Isoprene Polyelectrolyte”, Biomacromolecules 12, 1697 (2011)

› M. Nomikos, K. Elgmati, M. Theodoridou, B.L. Calver, G. Nounesis, K. Swann and F.A. Lai, “Phospholipase Cζ binding to Ptdlns(4,5)PIP2 requires the XY-linker region”, Journal of Cell Science 124, 2582 (2011)

› M. Nomikos, K. Elgmati, M. Theodoridou, B.L. Calver, B. Cumbes, G. Nounesis, K. Swann and F.A. Lai, “Male infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP2 hydrolysis activity of sperm PLCζ”, Biochemical Journal, accelerated publication 434, 211 (2011)
Paper selected for cover and BJ Central Spotlight, February - March 2011

› M. Nomikos, K. Elgmati, M. Theodoridou, A. Georgilis, G. Nounesis, K. Swann and F.A. Lai, “Novel regulation of PLCζ activity via its XY-linker”, Biochemical Journal, accelerated publication 438, 427 (2011)
Paper selected for cover and BJ Central Spotlight, September 2011

› E. Makarona, P. Petrou, A. Bourkoula, A. Botsialas, M. Kitsara, S. Kakabakos, R. Stoffer, G. Jobst, G. Nounesis, I. Raptis, Ioannis, K. Misiakos, "Monolithically integrated Mach-Zehnder biosensors for real-time label-free monitoring of biomolecular reactions," Engineering in Medicine and Biology Society, Annual International Conference of the IEEE, 7654 (2011))

› D. Tsiourvas, Z. Sideratou, N. Sterioti, A. Papadopoulos and G. Nounesis “Insulin complexes with PEGylated basic oligopeptides”, Journal of Colloid and Interface Science 384, 61 (2012)

› Y. Yu, M. Nomikos, M. Theodoridou, G. Nounesis, F.A. Lai and K. Swann, “PLCζ causes Ca2+ oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P2”, Molecular Biology of the Cell 23, 371 (2012)
Paper selected by Faculty of 1000, Post-publication peer review: Recommended

› B. Rozic, E. Karatairi, G. Nounesis, V. Tzitzios G. Cordoyiannis, S. Kralj and Z. Kutnjak, “Impact of Surface-Functionalized CdSe Nanoparticles on Phase Transitions of 8CB and CE8”, Molecular Crystals & Liquid Crystals 553, 161 (2012)

› M. Nomikos, Y. Yu, K. Elgmati, M. Theodoridou, K. Campbell, V. Vassilakopoulou, C. Zikos, E. Livaniou, N. Amso, G. Nounesis, K. Swann, and F.A. Lai, “Phospholipase Cζ rescues failed oocyte activation in a prototype of male factor infertility”, Fertility and Sterility 99, 76 (2013)

Links in BBC News Wales - www.medicalnews.com (commentary)

2013 Award, American Society of Reproductive Medicine (www.fertstert.org)

› Z. Karoulia, G. Papadopoulos, M. Nomikos, A. Thanassoulas, T.C. Papadopoulou, G. Nounesis, M. Kontou, C. Stathopoulos, D.D. Leonidas DD, “Studies on the essential intramolecular interaction between the A1 and A2 domains of von Willebrand factor”, Protein & Peptide Letters 20, 231 (2013)

› G. Cordoyiannis, V.S.R. Jampani, S. Kralj, S. Dhara, V. Tzitzios, G. Basina, G. Nounesis, Z. Kutnjak, C.S.P. Tripathi, P. Losada-Pérez, D. Jesenek, C. Glorieux, I. Muševič, A. Zidanšek, H. Amenitsch and J. Thoen, “Different modulated structures of topological defects stabilized by adaptive targeting nanoparticles”, Soft Matter 9, 3956 (2013)

› Z. Alexandrakis, G. Katsaros, P. Stavros, P. Katapodis, G. Nounesis and P. Taoukis, “Comparatives structural changes and inactivation kinetics of pectin methylesterases from two orange varieties subjected to high pressure processing”, Food and Bioprocess Technology, in press, published on-line 10.1007/s11947-013-1087-7(April, 2013)

› M. Lavric, G. Cordoyiannis, S. Kralj, V. Tzitzios, G. Nounesis and Z. Kutnjak, “Effect of anisotropic MoS2 nanoparticles on the blue phase range of a chiral liquid crystal”, Applied Optics 52, E47 (2013)

› L. Blayney, K. Beck, E. Macdonald, L. D'Cruz, M. Nomikos, J. Griffiths, A. Thanassoulas, G. Nounesis and F. A. Lai, “ATP interacts with the CPVT mutation-associated central domain of the cardiac ryanodine receptor”, Biochimica et Biophysica Acta 1830, 4426 (2013)

› M. Lavric, V. Tzitzios, S. Kralj, G. Cordoyiannis, G. Nounesis, V. Georgakilas, H. Amenitsch, A. Zidansek, I. Lelidis and Z. Kutnjak, “The eﬀect of graphene on liquid-crystalline blue phases”, Applied Physics Letters 103, 143116 (2013)

› A. Thanassoulas, E. Karatairi, G. Cordoyiannis, Z. Kutnjak, I. Lelidis, V. Tzitzios and G. Nounesis, “CdSe nanoparticles dispersed in ferroelectric smectic liquid crystals: Effects upon the smectic order and the smectic-A to chiral smectic-C phase transition”, Physical Review E, Statistical, Nonlinear and Soft Matter Physics 88, 032504 (2013)

› M. Theodoridou, M. Nomikos, J. R. Conzalez-Garcia, K. Elgmati, B. L. Calver, Z. Sideratou, G. Nounesis, K. Swann and F. A. Lai, “Chimeras of sperm PLCζ with PLCδ1 reveal discrete domain roles in the generation of Ca2+ oscillations at fertilization in mouse eggs”, Human Reproduction, in press, doi:10.1093/molehr/gat070 (2013)
Paper Selected for Editor’s Choice

› Sarantis Giatrellis and George Nounesis, “Interactions of DNA and RNA with Biomembranes, in Drug – Biomembrane Interaction Studies: The Application of Calorimetric Techniques, R. Pignatello Editor, Biohealthcare Publishing, Oxford, (2013)

› Dimitris Mastellos and George Nounesis, “The BRCT signaling “landscape”: Emerging concepts and implications in tumorigenesis and cancer diagnostics”, Chapter 6, pp 173 – 208, in Cancer Biomarkers, A. Georgakilas Editor, CRC Press, Boca Raton, (2013)

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